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1.
Cir Pediatr ; 36(1): 33-39, 2023 Jan 01.
Artículo en Inglés, Español | MEDLINE | ID: mdl-36629347

RESUMEN

INTRODUCTION: Varicocele is an abnormal dilatation of the internal spermatic veins of the spermatic cord. It has an estimated prevalence of 15% in young male adults. Even though most of them are asymptomatic, scrotal pain and testicular hypotrophy are frequent in children and adolescents. There is controversy regarding the indications and optimal approach for treatment purposes. We present the results of our 15-year series in the laparoscopic repair of pediatric varicocele. MATERIALS AND METHODS: 238 patients diagnosed with varicocele and undergoing laparoscopic repair from 2006 to 2020 were reviewed. Variables collected included age, symptoms, grade, testicular atrophy, hospital stay, perioperative complications, recurrences, and formation of reactive hydrocele. Mean follow-up was 5.6 years (6 months-9 years). RESULTS: Mean age was 14.1 years. 188 patients had grade III varicocele. In 14 cases, varicocele was bilateral. Testicular atrophy at diagnosis was found in 42% of patients, 74% of whom were over 15 years old. 51 patients had testicular pain. All patients underwent laparoscopic treatment. Mean operating time was 36 min. Median hospital stay was 31 h. Recurrence rate was 2.1%. 43 patients (18%) developed hydrocele, but only 27 (11.2%) required hydrocelectomy according to Lord's plication at least 1 year following laparoscopy. Of the remaining 16 cases, 2 spontaneously resolved and 14 remained stable in the mean 7-year follow-up. In 7.1%, paresthesias were noted in the anterior-internal aspect of the left thigh. CONCLUSION: Based on our series, we believe laparoscopy should be regarded as the gold standard technique in the pediatric population. Laparoscopic varicocelectomy is technically easy and fast, causes no pain, and has a recurrence rate of 1%. The procedures involving lymphatic vessel preservation could reduce reactive hydrocele rates as a long-term complication to a minimum.


INTRODUCCION: El varicocele es una dilatación anormal de las venas espermáticas internas del cordón espermático. Su prevalencia se estima en 15% de varones adultos jóvenes. Aunque la mayoría son asintomáticos, en niños y adolescentes el dolor escrotal y la hipotrofia testicular son frecuentes. Existe controversia sobre las indicaciones y el abordaje óptimo para su tratamiento. Presentamos los resultados de nuestra serie de 15 años en la reparación laparoscópica del varicocele pediátrico. MATERIAL Y METODOS: Revisamos 238 pacientes diagnosticados de varicocele y sometidos a corrección laparoscópica desde 2006 hasta 2020. Las variables registradas fueron: edad, síntomas, grado, atrofia testicular, duración de la estancia, complicaciones perioperatorias, recidivas y formación de hidrocele reactivo. El seguimiento medio fue 5,6 años (6 meses-9 años). RESULTADOS: La edad promedio fue 14,1 años. 188 pacientes presentaban varicocele grado III. En 14 casos el varicocele era bilateral. Se observó atrofia testicular en 42% al diagnóstico, de los que el 74% eran mayores de 15 años. Cincuenta y un pacientes refirieron dolor testicular. Todos los pacientes se sometieron al tratamiento laparoscópico. El tiempo operatorio promedio fue 36 min. La mediana de estancia fue 31 horas. La tasa de recidiva fue 2,1%. Cuarenta y tres pacientes desarrollaron hidrocele (18%); pero solo 27 precisaron hidrocelectomía según plicatura de Lord al menos un año poslaparoscopia (11,2%). De los 16 restantes, dos se resolvieron espontáneamente y 14 se mantuvieron estables en el seguimiento medio de siete años. En 7,1% se notificaron parestesias en la cara anterointerna del muslo izquierdo. CONCLUSION: Basándonos en nuestra serie, creemos que la laparoscopia debe considerarse el gold standard en edad pediátrica. La varicocelectomía laparoscópica es técnicamente fácil y rápida, indolora y con una tasa de recurrencia del 1%. Los procedimientos de preservación de los linfáticos podrían reducir al mínimo las tasas de hidrocele reactivo como complicación a largo plazo.


Asunto(s)
Laparoscopía , Enfermedades Testiculares , Hidrocele Testicular , Varicocele , Adolescente , Adulto , Humanos , Masculino , Niño , Varicocele/cirugía , Laparoscopía/métodos , Hidrocele Testicular/cirugía , Enfermedades Testiculares/etiología , Atrofia/etiología , Resultado del Tratamiento
2.
Cir. pediátr ; 36(1): 33-39, Ene. 2023. tab
Artículo en Español | IBECS | ID: ibc-214578

RESUMEN

Introducción: El varicocele es una dilatación anormal de las venas espermáticas internas del cordón espermático. Su prevalencia se estima en 15% de varones adultos jóvenes. Aunque la mayoría son asintomáticos, en niños y adolescentes el dolor escrotal y la hipotrofia testicular son frecuentes. Existe controversia sobre las indicaciones y el abordaje óptimo para su tratamiento. Presentamos los resultados de nuestra serie de 15 años en la reparación laparoscópica del varicocele pediátrico. Material y métodos: Revisamos 238 pacientes diagnosticados de varicocele y sometidos a corrección laparoscópica desde 2006 hasta 2020. Las variables registradas fueron: edad, síntomas, grado, atrofia testicular, duración de la estancia, complicaciones perioperatorias, recidivas y formación de hidrocele reactivo. El seguimiento medio fue 5,6 años (6 meses-9 años). Resultados: La edad promedio fue 14,1 años. 188 pacientes presentaban varicocele grado III. En 14 casos el varicocele era bilateral. Se observó atrofia testicular en 42% al diagnóstico, de los que el 74%eran mayores de 15 años. Cincuenta y un pacientes refirieron dolor testicular. Todos los pacientes se sometieron al tratamiento laparoscópico. El tiempo operatorio promedio fue 36 min. La mediana de estancia fue 31 horas. La tasa de recidiva fue 2,1%. Cuarenta y tres pacientes desarrollaron hidrocele (18%); pero solo 27 precisaron hidrocelectomía según plicatura de Lord al menos un año poslaparoscopia (11,2%). De los 16 restantes, dos se resolvieron espontáneamente y 14 se mantuvieron estables en el seguimiento medio de siete años. En 7,1% se notificaron parestesias en la cara anterointerna del muslo izquierdo. Conclusión: Basándonos en nuestra serie, creemos que la laparoscopia debe considerarse el gold standard en edad pediátrica. La varicocelectomía laparoscópica es técnicamente fácil y rápida, indolora y con una tasa de recurrencia del 1%...(AU)


Introduction: Varicocele is an abnormal dilatation of the internal spermatic veins of the spermatic cord. It has an estimated prevalence of 15% in young male adults. Even though most of them are asymptomatic, scrotal pain and testicular hypotrophy are frequent in children and adolescents. There is controversy regarding the indications and optimal approach for treatment purposes. We present the results of our 15-year series in the laparoscopic repair of pediatric varicocele. Materials and methods: 238 patients diagnosed with varicocele and undergoing laparoscopic repair from 2006 to 2020 were reviewed. Variables collected included age, symptoms, grade, testicular atrophy, hospital stay, perioperative complications, recurrences, and formation of reactive hydrocele. Mean follow-up was 5.6 years (6 months-9 years). Results: Mean age was 14.1 years. 188 patients had grade III varicocele. In 14 cases, varicocele was bilateral. Testicular atrophy at diagnosis was found in 42% of patients, 74% of whom were over 15 years old. 51 patients had testicular pain. All patients underwent laparoscopic treatment. Mean operating time was 36 min. Median hospital stay was 31 h. Recurrence rate was 2.1%. 43 patients (18%) developed hydrocele, but only 27 (11.2%) required hydrocelectomy according to Lord’s plication at least 1 year following laparoscopy. Of the remaining 16 cases, 2 spontaneously resolved and 14 remained stable in the mean 7-year follow-up. In 7.1%, paresthesias were noted in the anterior-internal aspect of the left thigh. Conclusion: Based on our series, we believe laparoscopy should be regarded as the gold standard technique in the pediatric population. Laparoscopic varicocelectomy is technically easy and fast, causes no pain, and has a recurrence rate of 1%. The procedures involving lymphatic vessel preservation could reduce reactive hydrocele rates as a long-term complication to a minimum.(AU)


Asunto(s)
Humanos , Masculino , Femenino , Niño , Adolescente , Varicocele , Pediatría , Laparoscopía , Prevalencia , Pacientes , Estudios Retrospectivos , Epidemiología Descriptiva
3.
Rev. esp. anestesiol. reanim ; 69(8): 487-492, Oct. 2022. tab
Artículo en Español | IBECS | ID: ibc-210288

RESUMEN

La dexmedetomidina (DEX) es un agente anestésico que mimetiza el sueño profundo natural y produce una mínima depresión cardiorrespiratoria, convirtiéndose en una opción muy valiosa en el manejo de un paciente tan exigente como es el pediátrico. El objetivo principal de esta mini revisión fue centrarse en el papel de la DEX como analgésico en el período perioperatorio de niños sometidos a anestesia. Se realizó una búsqueda bibliográfica, entre 2010 y 2021, en Google, Pubmed, Embase y Cochrane Library. Se repasaron diferentes aspectos como su farmacología, efectividad, seguridad y la evidencia más reciente sobre su uso clínico como analgésico en anestesia pediátrica. Igualmente se incluyó una estimación de coste del tratamiento analgésico perioperatorio con DEX.(AU)


Dexmedetomidine (DEX) is an anaesthetic agent that mimics natural deep sleep and produces minimal cardiorespiratory depression. As such, it is a very valuable option in the management of such a challenging population as paediatric patients. The main objective of this mini review was to evaluate the role of DEX as a perioperative analgesic in children receiving anaesthesia. We searched Google, Pubmed, Embase and the Cochrane Library for articles published between 2010 and 2021, and reviewed various of aspects of DEX, such as pharmacology, effectiveness, safety, and the most recent evidence on its clinical use as an analgesic in paediatric anaesthesia. We also include a cost estimate of perioperative analgesia with DEX.(AU)


Asunto(s)
Humanos , Lactante , Niño , Adolescente , Dexmedetomidina , Analgesia , Periodo Perioperatorio , Anestesia , Pediatría , Analgésicos , Manejo del Dolor , Farmacocinética , Bases de Datos Bibliográficas , PubMed , Reanimación Cardiopulmonar , Anestesiología
4.
Rev Esp Anestesiol Reanim (Engl Ed) ; 69(8): 487-492, 2022 10.
Artículo en Inglés | MEDLINE | ID: mdl-36100555

RESUMEN

Dexmedetomidine (DEX) is an anaesthetic agent that mimics natural deep sleep and produces minimal cardiorespiratory depression. As such, it is a very valuable option in the management of such a challenging population as paediatric patients. The main objective of this mini review was to evaluate the role of DEX as a perioperative analgesic in children receiving anaesthesia. We searched Google, Pubmed, Embase and the Cochrane Library for articles published between 2010 and 2021, and reviewed various of aspects of DEX, such as pharmacology, effectiveness, safety, and the most recent evidence on its clinical use as an analgesic in paediatric anaesthesia. We also include a cost estimate of perioperative analgesia with DEX.


Asunto(s)
Analgesia , Anestesia , Dexmedetomidina , Analgésicos , Niño , Dexmedetomidina/farmacología , Dexmedetomidina/uso terapéutico , Humanos
5.
Artículo en Inglés, Español | MEDLINE | ID: mdl-34049712

RESUMEN

Dexmedetomidine (DEX) is an anaesthetic agent that mimics natural deep sleep and produces minimal cardiorespiratory depression. As such, it is a very valuable option in the management of such a challenging population as paediatric patients. The main objective of this mini review was to evaluate the role of DEX as a perioperative analgesic in children receiving anaesthesia. We searched Google, Pubmed, Embase and the Cochrane Library for articles published between 2010 and 2021, and reviewed various of aspects of DEX, such as pharmacology, effectiveness, safety, and the most recent evidence on its clinical use as an analgesic in paediatric anaesthesia. We also include a cost estimate of perioperative analgesia with DEX.

6.
Radiología (Madr., Ed. impr.) ; 62(3): 188-197, mayo-jun. 2020. ilus, tab
Artículo en Español | IBECS | ID: ibc-194216

RESUMEN

OBJETIVOS: La región inguinal es un área anatómica compleja que ha sido tradicionalmente olvidada por los radiólogos dado que la mayoría de las lesiones pueden diagnosticarse mediante datos clínicos y con la exploración física. No obstante, cada vez es más frecuente la solicitud de ecografías, bien para confirmar la existencia de patología o para resolver casos dudosos. Por otra parte, la patología inguinal incluye entidades únicas de la edad infantil. El objetivo de este trabajo es describir los hallazgos radiológicos clave de las lesiones inguinales pediátricas, poniendo especial énfasis en los datos ecográficos CONCLUSIONES: El conocimiento de la patología inguinal pediátrica y sus claves en imagen ayudan a mejorar el rendimiento diagnóstico de la ecografía


OBJECTIVES: The groin is a complex anatomic region that has traditionally been ignored by radiologists because most lesions can be diagnosed from clinical data and physical examination. Nevertheless, ultrasound examinations of the groin are increasingly being requested to confirm injury or to resolve diagnostic uncertainty. On the other hand, some conditions involving the groin are found only in pediatric patients. This article describes the key imaging findings in pediatric groin injuries, placing special emphasis on the ultrasound appearance. CONCLUSIONS: Knowledge about conditions that can affect the groin in pediatric patients and the key imaging findings associated with them helps improve the diagnostic performance of ultrasound


Asunto(s)
Humanos , Lactante , Niño , Conducto Inguinal/diagnóstico por imagen , Conducto Inguinal/embriología , Conducto Inguinal/lesiones , Ultrasonografía , Criptorquidismo/diagnóstico por imagen , Linfadenopatía/diagnóstico por imagen , Lesiones del Sistema Vascular/diagnóstico por imagen , Conducto Inguinal/anatomía & histología , Hernia/diagnóstico por imagen , Hidrocele Testicular/diagnóstico por imagen
7.
Radiologia (Engl Ed) ; 62(3): 188-197, 2020.
Artículo en Inglés, Español | MEDLINE | ID: mdl-32165019

RESUMEN

OBJECTIVES: The groin is a complex anatomic region that has traditionally been ignored by radiologists because most lesions can be diagnosed from clinical data and physical examination. Nevertheless, ultrasound examinations of the groin are increasingly being requested to confirm injury or to resolve diagnostic uncertainty. On the other hand, some conditions involving the groin are found only in pediatric patients. This article describes the key imaging findings in pediatric groin injuries, placing special emphasis on the ultrasound appearance. CONCLUSIONS: Knowledge about conditions that can affect the groin in pediatric patients and the key imaging findings associated with them helps improve the diagnostic performance of ultrasound.


Asunto(s)
Conducto Inguinal/diagnóstico por imagen , Adolescente , Aneurisma Falso/diagnóstico por imagen , Niño , Preescolar , Criptorquidismo/diagnóstico por imagen , Femenino , Arteria Femoral/diagnóstico por imagen , Hamartoma/diagnóstico por imagen , Hernia Inguinal/congénito , Hernia Inguinal/diagnóstico por imagen , Humanos , Lactante , Recién Nacido , Conducto Inguinal/anatomía & histología , Lipoma/diagnóstico por imagen , Imagen por Resonancia Magnética/métodos , Masculino , Sarcoma/diagnóstico por imagen , Cordón Espermático/diagnóstico por imagen , Hidrocele Testicular/diagnóstico por imagen , Ultrasonografía/métodos , Venas/anomalías , Venas/diagnóstico por imagen
8.
Rev Esp Anestesiol Reanim (Engl Ed) ; 66(9): 459-466, 2019 Nov.
Artículo en Inglés, Español | MEDLINE | ID: mdl-31582277

RESUMEN

INTRODUCTION: Quality improvement in health care entails the design of reliable processes which prevent and mitigate medical errors. Checklists are cognitive tools which reduce such errors. The primary objective of this study was to design an anesthetic checklist in Pediatrics to be implemented in our hospital. METHODS: Delphi technique was used, with 3 rounds of questionnaire surveys: a generic questionnaire to obtain dimensions and items; and 2 specific ones to score individual items and obtain an overall rating for the checklist (median), and to measure the level of consensus (relative interquartile range) and internal reliability (Wilcoxon signed-rank test). RESULTS: Final version of the checklist obtained a high overall score (Med 9) with a very high consensus (RIR 5%). Internal consensus was reached on all items (RIR ≤ 30%). Wilcoxon signed-rank test found no statistically significant differences, demonstrating reliability or consistency of responses between consecutive rounds. CONCLUSION: The Anesthetic checklist in Pediatrics has been methodically designed for implementation and use in our hospital.


Asunto(s)
Anestesia/normas , Lista de Verificación/normas , Errores Médicos/prevención & control , Pediatría/normas , Mejoramiento de la Calidad , Lista de Verificación/métodos , Consenso , Técnica Delfos , Retroalimentación , Encuestas de Atención de la Salud/normas , Humanos , Seguridad del Paciente , Calidad de la Atención de Salud , Reproducibilidad de los Resultados , Estadísticas no Paramétricas , Encuestas y Cuestionarios/normas
9.
Artículo en Inglés, Español | MEDLINE | ID: mdl-31084978

RESUMEN

INTRODUCTION: Haemofiltration paradigms used to manage critically ill patients with a dysregulated inflammatory response (DIR) assess kidney function to monitor its onset, adaptation, and completion. A Continuous Venous Hyperfiltration (CONVEHY) protocol is presented, in which a non-specific adsorption membrane (AN69-ST-Heparin Grafted) is used with citrate as an anticoagulant and substitution fluid. CONVEHY uses tools readily available to achieve kidney related and non-related objectives, and it is guided by the monitoring of pathophysiological responses. OBJECTIVES: To compare the response to an AN69-ST-HG membrane when heparin (He, n=5: Standard protocol) or citrate (Ci, n=6: CONVEHY protocol) was used to evaluate whether a larger study into the benefits of this protocol would be feasible. MATERIALS AND METHODS: In a retrospective pilot study, the benefits of the CONVEHY protocol to manage patients with a DIR in a surgical critical care unit (CCUs) were assessed by evaluating the SOFA (Sequential Organ Failure Assessment) (He 11 ± 2.35; Ci 11 ± 3.63: p=0.54) and APACHE II (He 28.60 ± 9.40; Ci 24 ± 8.46: p=0.93) scores. RESULTS: Nights in hospital (He 35.2 ± 16.3 nights; Ci 9 ± 2.53: p=0.004), hospital admission after discharge from the CCUs (He 40.25 ± 21.82; Ci 13.2 ± 4.09: p=0.063), patients hospitalised >20 days (He 80%; Ci 0%: p=0.048), days requiring mechanical ventilation (He 16 ± 5.66; Ci 4 ± 1.72: p=0.004), and the predicted (55.39 ± 26.13%) versus real mortality in both groups (9.1%: p=0.004). CONCLUSIONS: The CONVEHY protocol improves the clinical responses of patients with DIR, highlighting the potential value of performing larger and confirmatory studies.


Asunto(s)
Anticoagulantes/uso terapéutico , Citratos/uso terapéutico , Terapia de Reemplazo Renal Continuo/métodos , Inflamación/terapia , Membranas Artificiales , Complicaciones Posoperatorias/terapia , APACHE , Adulto , Estudios de Casos y Controles , Protocolos Clínicos , Terapia de Reemplazo Renal Continuo/instrumentación , Enfermedad Crítica , Estudios de Factibilidad , Fluidoterapia , Heparina/uso terapéutico , Hospitalización/estadística & datos numéricos , Humanos , Inflamación/etiología , Puntuaciones en la Disfunción de Órganos , Proyectos Piloto , Complicaciones Posoperatorias/etiología , Estudios Retrospectivos , Tamaño de la Muestra , Procedimientos Quirúrgicos Operativos/efectos adversos
12.
J Hum Hypertens ; 31(2): 151-156, 2017 02.
Artículo en Inglés | MEDLINE | ID: mdl-27535123

RESUMEN

The aim of this study was to evaluate the relationship between early blood pressure (BP) changes (detected using ambulatory BP monitoring; ABPM) with different markers of inflammation and endothelial dysfunction in patients with type 1 diabetes mellitus (T1DM). The study design was observational cross-sectional in 85 T1DM patients, clinically normotensive and with normo-albuminuria. We analyzed the relationships between ABPM-measured BP alterations over 24 h with the inflammatory cytokines (interleukin-6 (IL-6), tumor necrosis factor-α and vascular endothelial growth factor (VEGF)) and the markers of endothelial damage (vascular adhesion molecule, intercellular adhesion molecule and plasminogen activator inhibitor-1 (PAI)). Despite being recorded as normotensive, 27 (31.8%) subjects presented with an average of pathological BP. VEGF levels were significantly elevated in the patients with an altered mean diurnal values compared with normotensives (112.33 (72.87-213.53) pg ml-1 vs 71.03 (37.71-107.92) pg ml-1; P=0.007). Further, VEGF levels correlated significantly with the parameters of diurnal BP and of 24 h values. IL-6 concentration was a risk factor in the patients with hypertension (OR=1.406; P=0.027). There were no modifications in the levels of markers of endothelial damage. Summarizing, there is an increase in pro-inflammatory cytokines, but not the endothelial adhesion molecules, in early stages of arterial hypertension in patients with T1DM.


Asunto(s)
Biomarcadores/sangre , Diabetes Mellitus Tipo 1/sangre , Inflamación/sangre , Hipertensión Enmascarada/sangre , Adulto , Estudios Transversales , Diabetes Mellitus Tipo 1/complicaciones , Femenino , Humanos , Inflamación/complicaciones , Masculino , Hipertensión Enmascarada/complicaciones , Análisis Multivariante , Adulto Joven
14.
Rev Esp Anestesiol Reanim ; 63(2): 91-100, 2016 Feb.
Artículo en Español | MEDLINE | ID: mdl-25866132

RESUMEN

Pediatric neuraxial anesthesia is an effective tool that can be used as a supplement or alternative to general anesthesia. However, there have always been doubts about its usefulness and risk-benefit ratio. The purpose of this review is to describe the current role of central blockades in pediatric patients, upgrade practical and safety aspects, and review the latest technological advances applied to this procedure.


Asunto(s)
Anestesia General , Anestesia de Conducción , Niño , Humanos , Medición de Riesgo
15.
Cir. pediátr ; 27(3): 149-152, jul. 2014. ilus
Artículo en Español | IBECS | ID: ibc-131767

RESUMEN

El infarto omental es una patología que se presenta cada vez más en los niños debido al mayor uso de los estudios de imagen y al incremento del sobrepeso y la obesidad. Clínicamente se caracteriza por doloren hemiabdomen derecho y puede confundirse con apendicitis, ileítis, adenitis, entre otros cuadros abdominales. Su diagnóstico definitivo requiere la realización de estudios de imagen y su tratamiento puede ser conservador. Presentamos 3 casos de infarto omental con diferente forma de presentación clínica, tratados con éxito de forma conservadora


The omental infarction is a pathology that occurs more and more in children due to the increased use of imaging studies and the increment in overweight and obesity. Clinical presentation is characterized by abdominal pain and can be confused with appendicitis, ileitis, adenitis,a mong other abdominal conditions. Definitive diagnosis requires the performance of radiologic investigations and its treatment may be conservative. We report three cases of omental infarction with different form of clinical presentation, successfully managed conservativel


Asunto(s)
Humanos , Masculino , Femenino , Niño , Infarto/diagnóstico , Epiplón , Cavidad Peritoneal , Tratamientos Conservadores del Órgano , Dolor Abdominal/etiología , Obesidad/complicaciones
16.
J Endocrinol Invest ; 37(6): 503-9, 2014 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-24458829

RESUMEN

BACKGROUND: Relationships between adhesion molecules (AM), oxidative stress, gestational diabetes mellitus (GDM) and future development of type 2 diabetes mellitus are unclear. AIM: We investigated AM and oxidant/antioxidant markers in women with previous history of GDM. SUBJECTS AND METHODS: Postpartum women with GDM (cases; n = 41) and healthy women (controls; n = 21) had clinical and laboratory variables measured, including indicators of vascular damage (ICAM-1, VCAM-1 and E-selectin), oxidative stress (LPO, GSH and GST) and antioxidant markers (catalase, SOD, GPX and TAC). RESULTS: Previous GDM versus control women presented higher body mass index: 27.4 ± 5.6 versus 23.9 ± 3.6 (p = 0.013); waist circumference: 85.2 ± 12.9 versus 77.5 ± 9.0 (p = 0.017); MetS (WHO definition): 14.6 versus 0 % (p = 0.012); MetS (NCEP-ATPIII definition): 22 versus 0 % (p = 0.002); low HDL: 36.6 versus 9.5 % (p = 0.024); fasting glucose (mmol/L): 5.4 ± 0.6 versus 4.9 ± 0.2 (p < 0.001); glucose 120 min (mg/dL): 105.0 ± 30.2 versus 85.1 ± 14.2 (p = 0.007); fasting insulin (µU/mL): 13.4 ± 8.1 versus 8.4 ± 4.3 (p = 0.004); HOMA index: 3.3 ± 2.3 versus 1.8 ± 1.0 (p = 0.002); HbA1c (%/mmol/mol): 5.4 ± 0.2 versus 5.2 ± 0.2/36 ± 1.4 versus 33 ± 1.4 (p = 0.021); uric acid (mg/dL): 4.1 ± 1 versus 3.5 ± 0.6 (p = 0.009); catalase (nmol/min/mL): 38.7 ± 15.6 versus 28.9 ± 11.1 (p = 0.013). There were no significant differences in hypertension prevalence, lipid fractions, albumin/creatinine ratio and AM. CONCLUSIONS: Women with previous GDM have high catalase levels which correlate positively with glucose intolerance, indicating the potential effect of oxidative stress on postpartum dysglycemic status.


Asunto(s)
Catalasa/sangre , Diabetes Gestacional/fisiopatología , Endotelio Vascular/fisiopatología , Estrés Oxidativo/fisiología , Periodo Posparto/metabolismo , Adulto , Antioxidantes/metabolismo , Biomarcadores/sangre , Glucemia/metabolismo , Diabetes Gestacional/metabolismo , Selectina E/sangre , Endotelio Vascular/metabolismo , Femenino , Prueba de Tolerancia a la Glucosa , Humanos , Insulina/sangre , Resistencia a la Insulina/fisiología , Molécula 1 de Adhesión Intercelular/sangre , Embarazo , Molécula 1 de Adhesión Celular Vascular/sangre
17.
Cir Pediatr ; 27(3): 149-52, 2014 Jul.
Artículo en Español | MEDLINE | ID: mdl-25845107

RESUMEN

The omental infarction is a pathology that occurs more and more in children due to the increased use of imaging studies and the increment in overweigth and obesity. Clinical presentation is characterized by abdominal pain and can be confused with appendicitis, ileitis, adenitis, among other abdominal conditions. Definitive diagnosis requires the performance of radiologic investigations and its treatment may be conservative. We report three cases of omental infarction with different form of clinical presentation, successfully managed conservatively.


Asunto(s)
Infarto/terapia , Epiplón/irrigación sanguínea , Niño , Femenino , Humanos , Masculino
18.
An Pediatr (Barc) ; 80(2): 106-13, 2014 Feb.
Artículo en Español | MEDLINE | ID: mdl-24103240

RESUMEN

INTRODUCTION: Bioethics has been recently incorporated in to the educational programs of both medical students and medical residents as part of their curriculum. However, its training based on clinical practice is not well structured. OBJECTIVE: To evaluate the knowledge of bioethics in Spanish paediatric residents, and to analyse how this relates to the medical education during graduate and post-graduate training. MATERIAL AND METHODS: A questionnaire with 20 multiple choice questions was designed to evaluate the knowledge in basic ethics with potential implications in clinical practice. We evaluated the education received during graduate and post-graduate training, and the main ethical conflicts faced. RESULTS: A total of 210 completed questionnaires were received from medical residents in paediatrics from 20 different Spanish hospitals, of whom 47 of these were first year residents (R1), 49 were second year residents (R2), 57 were third year residents (R3), and the remaining 57 were final year residents (R4). The mean number of correct answers was 16.8 out of 20. No differences were found between residents in different years of training, nor were there any differences between the group that had received specific training in bioethics versus those who had not. Residents were more likely to give wrong answers related with informed consent, the law on the freedom of the patient, principles of quality of life, the case analysis system, and the dimension of distributive justice. CONCLUSIONS: Limitation of therapeutic efforts was identified as the main ethical problem faced in clinical practice by Spanish residents in paediatrics. Most of the knowledge of bioethics is acquired during graduate training, and improved very little throughout the period of medical residence. Our results suggest that efforts are required in organising and structuring the education in bioethics during the training of residents in paediatrics.


Asunto(s)
Bioética/educación , Internado y Residencia , Pediatría/educación , Encuestas y Cuestionarios
19.
Clín. investig. ginecol. obstet. (Ed. impr.) ; 40(3): 136-138, mayo-jun. 2013. ilus
Artículo en Español | IBECS | ID: ibc-112357

RESUMEN

Los secuestros pulmonares son anomalías congénitas infrecuentes pero bien reconocidas. En los últimos años han mostrado un aumento de su incidencia en relación a los controles ecográficos rutinarios a los que son sometidas las gestantes. Por ello y a pesar de que representan tan solo entre el 0,15-6,45% de todas las malformaciones congénitas pulmonares constituyen entre el 8 y el 23% de los diagnósticos prenatales de anomalías pulmonares. El secuestro pulmonar extralobar infradiafragmático es una anomalía congénita extremadamente rara. La mayoría de estas lesiones se localizan en el hemiabdomen izquierdo siendo importante el diagnóstico diferencial con masas suprarrenales. El secuestro pulmonar debería ser considerado en todo neonato con masa abdominal superior o suprarrenal, sobre todo en casos de diagnóstico prenatal (AU)


Congenital lung sequestrations are uncommon but are well recognized. Recently, the incidence of these anomalies has increased due to routine ultrasound scans in pregnant women. Although these anomalies represent only 0,15% to 6,45% of all pulmonary malformations, they constitute between 8% and 23% of the prenatal diagnosis of lung abnormalities. Extralobar pulmonary sequestration is an extremely rare congenital infradiaphragmatic anomaly. Most of these lesions are located in the left abdomen and differential diagnosis with adrenal masses is essential. Pulmonary sequestration should be considered in any infant with an upper abdominal or adrenal mass, especially when diagnosis is prenatal (AU)


Asunto(s)
Humanos , Diagnóstico Prenatal/métodos , Secuestro Broncopulmonar/diagnóstico , Neoplasias Abdominales/diagnóstico
20.
Acta pediatr. esp ; 71(5): 133-133[e100-e103], mayo 2013. ilus
Artículo en Español | IBECS | ID: ibc-114101

RESUMEN

El neuroma es un crecimiento disperso y desordenado de las fibras nerviosas entremezcladas en tejido fibroso durante su proceso de regeneración. Es una patología poco común en la práctica clínica, y su diagnóstico en ocasiones resulta dificultoso y demorado en el tiempo. Presentamos el caso de una paciente de 13 años de edad con un cuadro de dolor abdominal incoercible y sin alteraciones en las pruebas diagnósticas realizadas, cuya causa resultó un neuroma en la cicatriz quirúrgica previa (AU)


The neuroma is a dispersed and disordered growth of the nervous fibers intermingled with fibrous tissue during its process of regeneration. It is a fairly uncommon pathology in the clinical practice and the diagnosis sometimes proves to be difficult and delayed in time. The author presents the clinical case of a 13-year-old patient with a severe abdominal pain, all diagnostic tests being normal without any alterations. The cause of the abdominal pain was a neuroma in a previous surgical scar (AU)


Asunto(s)
Humanos , Femenino , Adolescente , Neuroma/complicaciones , Neuroma/diagnóstico , Neuroma/patología , Dolor Abdominal/diagnóstico , Dolor Abdominal/etiología , Biopsia/instrumentación , Biopsia/métodos , Dolor Abdominal/complicaciones , Fibras Nerviosas/patología , Cicatriz/complicaciones , Cicatriz/patología , Cicatriz/cirugía , Neuroma/fisiopatología , Electrocoagulación/instrumentación , Electrocoagulación/métodos
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